ObjectiveTo investigate the effect of Ermiao Pills combined with fumigation and washing by modified Wuwei Xiaodu Drink for the adjuvant treatment of patients with pruritus ani (PA) in dampness-heat type.MethodsA total of 120 PA patients in dampness-heat type were selected, and they were randomly divided into study group or control group, with 60 cases in each group. The control group externally employed Mometasone Furoate Gel for treatment, based on which the study group was additionally treated with Ermiao Pills combined with fumigation and washing by modified Wuwei Xiaodu Drink. The pre- and post-treatment clinical syndrome score and score of life quality were compared between the two groups. The clinical efficacy after the end of treatment was compared between patients of the two groups. The occurrence of adverse reactions during treatment were recorded in both groups. ResultsAfter treatment, the scores for itching anus, skin lesions, perianal exudation, and Dermatology Life Quality Index scale scores in different dimensions in the two groups were decreased as compared with before treatment; moreover, the study group yielded lower scores for itching anus, skin lesions, perianal exudation, and lower scores in dimensions for daily activities, leisure, work and study as compared with the control group (P＜0.05). The total clinical effective rate in the study group was higher than that in the control group, and the total incidence rate of adverse reactions during treatment in the study group was lower than that in the control group (P＜0.05). ConclusionEmploying Ermiao Pills combined with fumigation and washing by modified Wuwei Xiaodu Drink for the adjuvant treatment of PA patients in dampness-heat type can ameliorate clinical symptoms of itching anus, skin lesions, perianal exudation, and improve clinical efficacy and quality of life, exerting a favorable safety, which is worthy of clinical application and promotion.

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