ObjectiveTo investigate the application effect of ultrasound-guided brachial plexus block via costoclavicular space approach in upper extremity fracture surgery. MethodsA total of 80 patients receiving upper extremity fracture surgery of ultrasound-guided brachial plexus block were randomly divided into via costoclavicular space approach group (CC group) or via coracoid approach group (CA group), with 40 cases in each group. Status of brachial plexus block, postoperative analgesia conditions, occurrence of postoperative adverse reactions were compared between patients of the two groups. ResultsThe CC group exhibited shallower puncture depth of brachial plexus block as compared with the CA group, shorter block operation duration and onset time as compared with the CA group (P<0.05); moreover, higher successful rates of comprehensive block in various time points except for 5 and 30 minutes after nerve block operation as compared with the CA group (P<0.05). After 12, 18, 24, and 36 hours of operation, the CC group yielded lower Visual Analogue Scale score for pain in resting state and motor state as compared with the CA group (P<0.05). There was no statistically significant difference in the total incidence rate of adverse reactions between the two groups (P>0.05). ConclusionEmploying ultrasound-guided brachial plexus block via costoclavicular space approach in upper extremity fracture surgery has advantages of easy and simple operation, rapid onset, favorable analgesic effect, and a low incidence rate of adverse reactions, etc.