ObjectiveTo explore the effect of transcranial direct current stimulation combined with mirror therapy for the treatment of patients with upper limb motor dysfunction after cerebral stroke. MethodsA total of 142 patients with upper limb motor dysfunction after cerebral stroke were randomly assigned to control group or research group, with 71 cases in each group. On the basis of routing rehabilitation therapy, the control group received transcranial direct current stimulation for treatment, whereas the research group was treated with transcranial direct current stimulation combined with mirror therapy. Both groups was treated for 6 weeks. The central motor conduction time (CMCT), motor evoked potential cortical latency, Fugl-Meyer Assessment for the Upper Extremity (FMA-UE) score, Barthel index score, Wolf Motor Function Test (WMFT) scale score, and quality of life were compared between patients of the two groups before and after treatment. ResultsAfter 6 weeks of treatment, both groups exhibited shorter motor evoked potential cortical latency and CMCT as compared with before treatment, whereas a elevated score of quality of life in various dimension as compared with before treatment, and the research group interpreted superior aforesaid indices to compared with the control group (P＜0.05). After 3 and 6 weeks of treatment, both groups indicated elevated scores of FMA-UE, Barthel index, and WMFT scale as compared with before treatment, and the research group yielded higher scores as above as compare with the control group (P＜0.05). ConclusionTranscranial direct current stimulation combined with mirror therapy can effectively ameliorate cortical excitability of the affected side in patients with upper limb motor dysfunction after cerebral stroke, and improve upper limb motor function, hand movement function, ability of daily living activities, and quality of life.

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