ObjectiveTo visually analyzed the research on minority medicine for the treatment of knee osteoarthritis (KOA) in China based on CiteSpace, so as to provide references for minority medicine in the treatment of KOA. MethodsLiterature related to 7 minority medicines (Mongolian Medicine, Uyghur Medicine, Zhuang Medicine, Yao Medicine, Tibetan Medicine, Miao Medicine, and Dai Medicine) for the treatment of KOA from 2000 to 2023 was retrieved from China National Knowledge Infrastructure, Wanfang Database Knowledge Service Platform, and VIP databases. The CiteSpace 6.2.R2 software was used to visually analyze the annual number of publications, authors, institutions, and keywords of the enrolled literature, and to draw a mapping knowledge domain. ResultsA total of 527 literature was enrolled to analyze, from 2000 to 2023, the annual number of publications for minority medicine in the treatment of KOA in China exhibited an overall upward trend. Uyghur Medicine, Miao Medicine, Mongolian Medicine, and Zhuang Medicine had initially formed a author cooperative group, and academic research results in this field were mainly concentrated in a few universities and their affiliated hospitals, and the cooperation between institutions in the same region was relatively close, while the cooperation between cross-regional institutions were less. A total of 10 cluster keywords in terms of clinical efficacy, sodium hyaluronate, Mongolian Medicine, etc.,and 21 burstness keywords with respect to osteoarthritis, knee joint, sand therapy, etc., were obtained. ConclusionClinical efficacy, sodium hyaluronate, and Mongolian Medicine, etc., are the research hotspots in the field of minority medicine for the treatment of KOA. The mechanism of action, operation standards, and efficacy evaluation are the research directions that have received close attention. However, there is little cooperation between cross-regional institutions, and there is still a lot of room for improvement.

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