Objective To construct the standard indices and processes of multidisciplinary combination therapy for diabetic foot (DF) and concomitant diabetic nephropathy (DN). Methods The first draft of standard indices and processes of multidisciplinary combination therapy for DF and concomitant DN was composed and then the expert letter consultation was formed through the methods of literature retrieving and group discussion, etc. The Delphi method was used to perform 3⁃round expert letter consultations for determining the standard indices of multidisciplinary combination therapy for DF and concomitant DN; furthermore, the processes of multidisciplinary combination therapy for DF and concomitant DN was finally determined by expert demonstration meeting. Results The effective recovery rates of questionnaire for 3⁃round expert letter consultations were all larger than 90%, and the expert authority coefficients were all larger than 0.70. The Kendall coordinate coefficients of first⁃level and second⁃level indices were 0.268 and 0.314 after 3 rounds of letter consultation, respectively, and variable coefficients were 0.084-0.151, and 0.093-0.189, respectively. The final standard indices and processes of multidisciplinary combination therapy for DF and concomitant DN formed contained 9 first⁃level indices, 61 second⁃level indices, and flow chart was formed on the basis of expert demonstration meeting. Conclusion The standard indices and processes of multidisciplinary combination therapy for DF and concomitant DN constructed in this study exert scientific, reliable and applicability to a certain extent, which can provide framework for the integrated management of patients with DF and concomitant DN.