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论著·临床研究 | 更新时间:2023-12-22
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急性心肌梗死后心力衰竭患者运动能力的影响因素及列线图预测模型的构建
Influencing factors for exercise ability in patients with heart failure after acute myocardial infarction and the establishment of nomogram prediction model

广西医学 2023第45卷19期 页码:2335-2342

作者机构:韦静,本科,主管护师,护士长,研究方向为心血管疾病护理。

基金信息:广西科技计划项目(桂科AB22080079);广西壮族自治区卫生健康委员会自筹经费科研课题(Z20210787)

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  • 英文简介
  • 参考文献
目的探讨急性心肌梗死后心力衰竭患者运动能力及其影响因素,并构建列线图预测模型。方法选择315例急性心肌梗死后心力衰竭患者作为研究对象,按调查先后顺序将其分为建模组221例和验证组94例。给予所有患者心肺运动试验,根据是否存在波浪式呼吸(OB)将建模组患者分为OB阳性组(n=85)和OB阴性组(n=136)。采用Logistic回归模型分析急性心肌梗死后心力衰竭患者运动能力的影响因素,基于影响因素构建列线图预测模型并进行验证。结果315例急性心肌梗死后心力衰竭患者OB阳性率为39.37%。多因素Logistic回归分析结果显示,合并慢性病种类、体质指数、美国纽约心脏病学会(NYHA)心功能分级、中文版心脏病运动恐惧量表(TSK-Heart-C)评分、冠心病患者康复运动知信行问卷评分、中文版简化版疾病感知问卷(B-IPQ)评分是急性心肌梗死后心力衰竭患者运动能力的独立影响因素(P<0.05)。基于上述影响因素构建的列线图预测模型具有较好的区分度、校准度。决策曲线分析结果显示,当阈值概率分别为2%~88%、1%~95%时,该模型预测急性心肌梗死后心力衰竭患者运动能力的净获益值较高。结论急性心肌梗死后心力衰竭患者运动能力较弱,合并慢性病种类、体质指数、NYHA心功能分级、TSK-Heart-C评分、冠心病患者康复运动知信行问卷评分、中文版B-IPQ评分是急性心肌梗死后心力衰竭患者运动能力的独立影响因素。基于上述影响因素构建的列线图预测模型有助于临床医师评估该人群的运动能力。
ObjectiveTo explore the exercise ability and its influencing factors in patients with heart failure after acute myocardial infarction, and to establish a nomogram prediction model. MethodsA total of 315 patients with heart failure after acute myocardial infarction were selected as the research subjects, and they were assigned to modeling group (221 cases) or validation group (94 cases) according to sequence of investigation. All patients received cardiopulmonary exercise testing, according to the presence of oscillatory breathing (OB), patients in the modeling group were divided into OB positive group (n=85) or OB negative group (n=136). The influencing factors for exercise ability in patients with heart failure after acute myocardial infarction were analyzed by using the Logistic regression model, and based on these influencing factors, the nomogram prediction model was established and validated. ResultsThe positive rate of OB was 39.37% among 315 patients with heart failure after acute myocardial infarction. The results of multivariate Logistic regression analysis revealed that categories of concomitant chronic diseases, body mass index, New York Heart Association (NYHA) cardiac function classification, the Chinese version of Tampa Scale for Kinesiophobia Heart (TSK-Heart-C) score, score of knowledge-belief-practice questionnaire of rehabilitation exercise in patients with coronary heart disease, and Chinese version Brief Illness Perception Questionnaire (B-IPQ) score were the independent influencing factors for exercise ability in patients with heart failure after acute myocardial infarction (P<0.05). The nomogram prediction model established based on the aforementioned influencing factors exerted favorable discrimination and calibration. The results of decision curve analysis indicated that when the threshold probabilities were 2%-88% and 1%-95%, respectively, the net benefit value of the model in predicting exercise ability in patients with heart failure after acute myocardial infarction was relatively high. ConclusionThe exercise ability of patients with heart failure after acute myocardial infarction is weak. Categories of concomitant chronic diseases, body mass index, NYHA cardiac function classification, TSK-Heart-C score, score of knowledge-belief-practice questionnaire of rehabilitation exercise in patients with coronary heart disease, and Chinese version B-IPQ score are the independent influencing factors for exercise ability in patients with heart failure after acute myocardial infarction. The nomogram prediction model established based on the influencing factors as above is helpful for clinicians to evaluate the exercise ability of this population.

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