Influencing factors for exercise ability in patients with heart failure after acute myocardial infarction and the establishment of nomogram prediction model
ObjectiveTo explore the exercise ability and its influencing factors in patients with heart failure after acute myocardial infarction, and to establish a nomogram prediction model. MethodsA total of 315 patients with heart failure after acute myocardial infarction were selected as the research subjects, and they were assigned to modeling group (221 cases) or validation group (94 cases) according to sequence of investigation. All patients received cardiopulmonary exercise testing, according to the presence of oscillatory breathing (OB), patients in the modeling group were divided into OB positive group (n=85) or OB negative group (n=136). The influencing factors for exercise ability in patients with heart failure after acute myocardial infarction were analyzed by using the Logistic regression model, and based on these influencing factors, the nomogram prediction model was established and validated. ResultsThe positive rate of OB was 39.37% among 315 patients with heart failure after acute myocardial infarction. The results of multivariate Logistic regression analysis revealed that categories of concomitant chronic diseases, body mass index, New York Heart Association (NYHA) cardiac function classification, the Chinese version of Tampa Scale for Kinesiophobia Heart (TSK-Heart-C) score, score of knowledge-belief-practice questionnaire of rehabilitation exercise in patients with coronary heart disease, and Chinese version Brief Illness Perception Questionnaire (B-IPQ) score were the independent influencing factors for exercise ability in patients with heart failure after acute myocardial infarction (P<0.05). The nomogram prediction model established based on the aforementioned influencing factors exerted favorable discrimination and calibration. The results of decision curve analysis indicated that when the threshold probabilities were 2%-88% and 1%-95%, respectively, the net benefit value of the model in predicting exercise ability in patients with heart failure after acute myocardial infarction was relatively high. ConclusionThe exercise ability of patients with heart failure after acute myocardial infarction is weak. Categories of concomitant chronic diseases, body mass index, NYHA cardiac function classification, TSK-Heart-C score, score of knowledge-belief-practice questionnaire of rehabilitation exercise in patients with coronary heart disease, and Chinese version B-IPQ score are the independent influencing factors for exercise ability in patients with heart failure after acute myocardial infarction. The nomogram prediction model established based on the influencing factors as above is helpful for clinicians to evaluate the exercise ability of this population.