广西医学

目的探讨郑氏2号熏洗方联合皮牵引辅助治疗湿热阻络型髋关节滑膜炎患儿的临床效果及安全性。方法将126例湿热阻络型髋关节滑膜炎患儿随机分为对照组和联合组，各63例。对照组采用皮牵引治疗，联合组采用皮牵引联合郑氏2号熏洗方治疗。比较两组患儿治疗前后Wong-Baker面部表情疼痛量表评分、治疗结束时的临床疗效、治疗前后血清炎症因子［白细胞介素（IL）-1β、IL-6、肿瘤坏死因子 α（TNF-α）］水平、治疗期间不良反应发生率及随访期间的复发情况。结果两组患儿的Wong-Baker面部表情疼痛量表评分均有随治疗时间的延长而降低的趋势，且治疗1周后及2周后联合组患儿的评分低于对照组（均P＜0.05）。联合组的总有效率为96.83%，高于对照组的85.71%（P＜0.05）。治疗后，两组患儿的血清IL-1β、IL-6、TNF-α水平均低于治疗前，且联合组患儿的上述指标水平均低于对照组（均P＜0.05）。随访期间，两组患儿病情均未复发；治疗期间，两组患儿的不良反应发生率差异无统计学意义（P＞0.05）。结论与单纯皮牵引治疗相比，郑氏2号熏洗方联合皮牵引辅助治疗湿热阻络型髋关节滑膜炎患儿的临床疗效更佳，可更好地缓解患儿疼痛，减轻机体炎症反应，且安全性较高。

ObjectiveTo explore the clinical effect and safety of Zheng′s No.2 fumigation and washing prescription combined with skin traction for the adjuvant treatment of children with hip synovitis in meridians obstructed by dampness-heat type. MethodsA total of 126 children with hip synovitis in meridians obstructed by dampness-heat type were randomly divided into control group or combined group, with 63 cases in each group. The control group was treated with skin traction, and the combined group was treated with skin traction combined with Zheng′s No.2 fumigation and washing prescription. The pre- and post-treatment Wong-Baker faces pain scale score, clinical efficacy at the end of treatment, pre- and post-treatment levels of serum inflammatory factors with respect to interleukin (IL)-1β, IL-6, tumor necrosis factor α (TNF-α), and incidence rate of adverse reactions during treatment, as well as recurrence during follow-up were compared between children of the two groups. ResultsThe Wong-Baker faces pain scale score of the two groups was decreased with increased treatment time, and the score of children in the combined group after 1 and 2 weeks of treatment was lower than that in the control group (all P＜0.05). The total effective rate of the combined group was 96.83%, which was higher than that of the control group (85.71%, P＜0.05). After treatment, the levels of serum IL-1β, IL-6, and TNF-α in the two groups were lower than those before treatment, and the levels of the above indices in the combined group were lower than those in the control group (all P＜0.05). During follow-up, no children relapsed in both groups, and there was no statistically significant difference in the incidence rate of adverse reactions between the two groups during treatment (P＞0.05). ConclusionCompared with single skin traction therapy, Zheng′s No.2 fumigation and washing prescription combined with skin traction for the adjuvant treatment of children with hip synovitis in meridians obstructed by dampness-heat type has superior clinical efficacy, which can preferably relieve children′s pain, and alleviate body inflammatory responses, exerting a relatively high safety.