ObjectiveTo analyze the improvement effect of day surgery management and settlement mode based on the two categories of surgery. MethodsA total of 263 patients undergoing day surgery admitted from January to December 2012 were selected as control group, and 210 patients receiving day surgery admitted from December 2021 to May 2022 were selected as observation group. In the control group and the observation group, 97 and 61 patients underwent adult tension-free hernia repair (unilateral) via local anesthesia, and 166 and 149 patients underwent laparoscopic cholecystectomy via general anesthesia, respectively. The control group received routine day surgery management and settlement mode, whereas the observation group optimized day surgery management mode based on the multidisciplinary surgery platform, concept of enhanced recovery after surgery and PDCA theory, and implemented the integration of electronic invoice and discharge rapid settlement on the basis of improving the construction of "Internet + healthcare". The constituent ratio and change rate of various expenses of the two categories of day surgery, as well as per capita discharge expense settlement time and patient settlement satisfaction were compared between patients of the two groups. ResultsIn adult tension-free hernia repair (unilateral), compared with the control group, medicine expense, material expense, bed expense, and other expenses of the observation group were reduced, operation expense, anesthesia expense, laboratory examination expense, treatment expense, and nursing expense were increased, whereas the per capita hospitalization expense and patients′ self-medical burden were reduced. In laparoscopic cholecystectomy, compared with the control group, drug expense, laboratory examination expense, material expense, and other expenses of the observation group were reduced, operation expense, anesthesia expense, treatment expense, bed expense, nursing expense, and per capita hospitalization expense were increased, but patients′ self-medical burden was decreased. The per capita discharge expense settlement time of the observation group was shorter than that of the control group, and the settlement satisfaction of patients was higher than that of the control group (P<0.05). ConclusionImproving day surgery management and settlement mode can optimize the composition of hospitalization expenses, better reflect labor value of medical staff, reduce medical burden of patients themselves, shorten settlement time of discharge expense, and improve the settlement satisfaction of patients.