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论著·临床研究 | 更新时间:2023-11-14
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最大标准摄取值与甲状腺癌患者临床病理特征的关系及其对预后的评估价值
Relation of maximum standard uptake value with clinicopathological features of patients with thyroid carcinoma and its estimated value for prognosis

广西医学 2023第45卷17期 页码:2083-2086+2110

作者机构:陈正福,硕士,副主任医师,研究方向:临床核医学。

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目的探讨18F-氟代脱氧葡萄糖(18F-FDG)PET-CT检查的最大标准摄取值与甲状腺癌患者临床病理特征的关系及其对预后的评估价值。方法选取88例甲状腺癌患者,对其进行18F-FDG PET-CT检查,比较甲状腺癌组织和癌旁组织18F-FDG PET-CT的最大标准摄取值,以及不同临床病理特征患者甲状腺癌组织的最大标准摄取值。分析最大标准摄取值与肿瘤直径的相关性。比较不同最大标准摄取值患者的预后。结果甲状腺癌组织最大标准摄取值为(5.37±1.12),癌旁组织最大标准摄取值为(1.61±0.34),甲状腺癌组织最大标准摄取值高于癌旁组织(P<0.05)。肿瘤直径>1 cm、有淋巴结转移甲状腺癌患者的最大标准摄取值高于肿瘤直径≤1 cm、无淋巴结转移患者(P<0.05)。Pearson相关性分析结果显示,甲状腺癌患者最大标准摄取值与肿瘤直径呈正相关(P<0.05)。癌组织中高最大标准摄取值的甲状腺癌患者生存率低于低最大标准摄取值的患者(P<0.05)。结论甲状腺癌患者癌组织18F-FDG PET-CT的最大标准摄取值升高,最大标准摄取值与肿瘤直径及患者预后密切相关。
ObjectiveTo explore the relation of maximum standard uptake value detected by 18F-fludeoxyglucose (FDG) PET-CT with clinicopathological features of patients with thyroid carcinoma and its estimated value for prognosis. MethodsA total of 88 patients with thyroid cancer were selected for 18F-FDG PET-CT examination. The maximum standard uptake value of 18F-FDG PET-CT was compared between thyroid cancerous tissues and paracancerous tissues, and between patients with different clinicopathological characteristics in thyroid cancerous tissues. The correlation of the maximum standard uptake value with tumor diameter was analyzed. The prognosis was compared between patients with different maximum standard uptake values. ResultsThe maximum standard uptake value of thyroid cancerous tissues was 5.37±1.12, 1.61±0.34 went to paracancerous tissues, and the maximum standard uptake value of thyroid cancerous tissues was larger than that of paracancerous tissues (P<0.05). Thyroid carcinoma patients with tumor diameter larger than 1 cm and lymph nodes metastasis obtained a higher maximum standard uptake value as compared with patients with tumor diameter ≤1 cm and without lymph nodes metastasis (P<0.05). The results of Pearson correlation analysis revealed that the maximum standard uptake value of patients with thyroid carcinoma positively correlated with tumor diameter (P<0.05). The survival rate of thyroid carcinoma patients with high maximum standard uptake value in cancerous tissues was lower than that with low maximum standard uptake value (P<0.05). ConclusionThe maximum standard uptake value of 18F-FDG PET-CT in cancerous tissues is elevated in patients with thyroid carcinoma, and the maximum standard uptake value is closely related to tumor diameter and patients′ prognosis.

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