ObjectiveTo explore the relation of maximum standard uptake value detected by 18F-fludeoxyglucose (FDG) PET-CT with clinicopathological features of patients with thyroid carcinoma and its estimated value for prognosis. MethodsA total of 88 patients with thyroid cancer were selected for 18F-FDG PET-CT examination. The maximum standard uptake value of 18F-FDG PET-CT was compared between thyroid cancerous tissues and paracancerous tissues, and between patients with different clinicopathological characteristics in thyroid cancerous tissues. The correlation of the maximum standard uptake value with tumor diameter was analyzed. The prognosis was compared between patients with different maximum standard uptake values. ResultsThe maximum standard uptake value of thyroid cancerous tissues was 5.37±1.12, 1.61±0.34 went to paracancerous tissues, and the maximum standard uptake value of thyroid cancerous tissues was larger than that of paracancerous tissues (P<0.05). Thyroid carcinoma patients with tumor diameter larger than 1 cm and lymph nodes metastasis obtained a higher maximum standard uptake value as compared with patients with tumor diameter ≤1 cm and without lymph nodes metastasis (P<0.05). The results of Pearson correlation analysis revealed that the maximum standard uptake value of patients with thyroid carcinoma positively correlated with tumor diameter (P<0.05). The survival rate of thyroid carcinoma patients with high maximum standard uptake value in cancerous tissues was lower than that with low maximum standard uptake value (P<0.05). ConclusionThe maximum standard uptake value of 18F-FDG PET-CT in cancerous tissues is elevated in patients with thyroid carcinoma, and the maximum standard uptake value is closely related to tumor diameter and patients′ prognosis.