ObjectiveTo systematically evaluate the effectiveness and safety of 3D printing technique combined with percutaneous nephrolithotomy (PCNL) for the treatment of kidney calculus. MethodsThe randomized controlled trials and/or case-control trials concerning 3D printing technique combined with PCNL for the treatment of kidney calculus were retrieved from the China National Knowledge Infrastructure, VIP smart cube, Wanfang Data Knowledge Service Platform, PubMed, The Cochrane Library, Embase, Web of Science and other databases. The search period was from establishment to March 8, 2021. After literature screening and quality evaluation, the RevMan 5.4 software was used for Meta-analysis. ResultsA total of 9 literature was finally enrolled. The results of Meta-analysis revealed that the observation group yielded higher stone clearance rate and success rate of one-time puncture, whereas shorter length of hospital stay, a lower incidence rate of complications, and less intraoperative bleeding volume as compared with the control group (all P＜0.05), but there was no statistically significant difference in operation duration between the two groups (P＞0.05). Conclusion3D printing technique combined with PCNL can improve the stone clearance rate and success rate of one-time puncture in patients with kidney calculus, shorten length of hospital stay, decrease the incidence rate of complications and intraoperative bleeding volume, exerting superior effect to PCNL application alone.

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