Objective To establish the systematic nursing regimen for continuous renal replacement therapy (CRRT) in patients with early cardiac surgery⁃associated acute kidney injury (CSA⁃AKI). Methods The CRRT systematic nursing regimen of early CSA⁃AKI patients was preliminary established by using the methods of literature analysis and group discussion, etc. Based on the Delphi method, items of regimen were determined through the expert letter consultation, and the weight of items was determine by using the analytic hierarchy process. Results The effective rate of questionnaire recycling in two⁃round expert letter consultation was all 100%, and the authority coefficient of the first and second rounds of expert letter consultation was 0.888 and 0.909, respectively. The mean importance scores of various third⁃level items ranged from 3.84 to 4.84, and 4.10 to 5.00, respectively, and the standard deviation ranges were 0.43-1.20 and 0-0.61, respectively, whereas the Kendall coordination coefficient was 0.124 and 0.158, respectively (P<0.05). Eventually, the determined systematic nursing regimen contained 4 first⁃level items, 15 second⁃level items, and 41 third⁃level items, and the consistency ratio of all⁃level items was less than 0.1. Conclusion CRRT systematic nursing regimen established for patients with early CSA⁃AKI patients can provide the reference basis for clinical practice.

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