Objective To explore the application value of laparoscopic technique for the diagnosis and treatment of infants with obstructive jaundice. Methods The clinical data of 51 infants with obstructive jaundice were retrospectively analyzed. All infants received laparoscopic minimally invasive exploration and cholangiography. According to the examination results, infants with cholestasis and biliary dysplasia all underwent biliary irrigation via gallbladder fistulization tube, and children with biliary atresia received Kasai biliary reconstruction surgery. The levels of direct bilirubin, ALT, AST before surgery, and 1, 2, 3, 4 weeks and 2 months after surgery were compared between infants with cholestasis and biliary dysplasia. Jaundice disappearance of infants with biliary atresia was recorded. Results There were 17 cases of biliary atresia, 32 cases of cholestasis, and 2 cases of biliary dysplasia among 51 infants with obstructive jaundice. Infants with cholestasis obtained lower levels of direct bilirubin, ALT 2, 3, 4 weeks and 2 months after surgery as compared with before surgery, and a lower AST level 4 weeks and 2 months after surgery as compared with before surgery (P<0.05). After 2 months of surgery, 2 infants with biliary dysplasia obtained decreased levels of direct bilirubin, ALT, and AST as compared with before surgery to varying degrees. A total of 12 infants with biliary atresia underwent Kasai biliary reconstruction surgery, and there were 9 cases of satisfactory disappearance of jaundice, and 3 cases of insignificant disappearance after surgery. Conclusion For infants with obstructive jaundice over 30 days of age, laparoscopic biliary exploration and cholangiography should be performed as soon as possible when conservative treatment by internal medicine system is ineffective, so as to elevate diagnostic accuracy, and perform treatment as soon as possible, thereby ameliorating infants' prognosis.

无