Objective To understand the scientific research status and influencing factors for groups of Chinese hospital clinicians, and to explore the planning and construction of clinical scientific research talents under the background of high⁃quality development. Methods A total of 8 provinces/autonomous regions/municipalities directly under the central government from Eastern, Central, and Western China were selected, and 40 hospitals were enrolled by using the stratified cluster sampling method. Hospital types included provincial/municipal/county public general hospitals, public hospitals of Chinese Medicine, and private hospitals. The status of scientific research works carried out by clinicians was investigated. The binary Logistic regression model was applied to analyze the influencing factors for scientific research works participated by clinicians, and to analyze the awareness status of clinicians on scientific research difficulties. Results A total of 3274 clinicians were enrolled, 50.3% of clinicians participated in scientific research works, 91.3% of clinicians had clear career development planning, therein 47.2% of clinicians regarded scientific research works as their primary choice for career development. Gender, age, technical titles, hospital types, hospital levels, approval of the achievement representative system in the professional title evaluation of health technical personnel, and career development opportunities and platforms might affect the status of scientific research works participated by clinicians (P<0.05). The main problems faced by clinicians in the process of carrying out scientific research works were heavy clinical works (accounting for 86.9%), followed by the lack of research teams (accounting for 56.4%), and the disconnect between scientific research and clinical practice (accounting for 55.4%). Conclusion Clinician groups in China have a clear career development planning, but their participation in scientific research works is generally limited, and they are faced with such limiting factors as “heavy clinical works” and “lack of research teams”. It is suggested that class Ⅱ/Ⅲ public hospitals should take scientific and technological innovation as a key task, pay attention to the important supporting role of scientific research works on the high⁃quality development of medical services, and continue to promote the construction of research⁃oriented hospitals. Public hospitals should establish and improve the planning of scientific research talents, and improve the training, use, evaluation, and incentive mechanism of scientific and technological talents.

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