The incidence rate of allergic diseases is increasing year by year, and environmental factors play an important role in it. Different exposure factors, dietary structure, and living environment exert crucial effects on the colonization and change of intestinal flora in the body. The abundance, composition and metabolites of intestinal flora can interact with the host immune system in skin, digestive tract, respiratory tract, and other parts of the body through immune, metabolic, neuroendocrine, and other pathways, which exert a lasting impact on the type, severity and duration of allergic diseases. This paper reviews the relation of intestinal flora with allergic diseases.

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