Objective To explore the effect of Dunstan baby language (DBL) curriculum learning on the incidence rate of suspected depression in puerperae and subjective well⁃being in puerperae and their husbands. Methods A total of 229 puerperae and their husbands were selected as the research subjects, and they were randomly assigned to intervention group (113 cases) or control group (116 cases). Puerperae and their husbands of the control group received routine curriculum of pregnant women, based on which the intervention group received additionally DBL curriculum learning. Occurrence states of suspected depression in puerperae after 42 days and 3 months of delivery, as well as subjective well⁃being scores in puerperae and their husbands after 7 days, 42 days, and 3 months of delivery were compared between the two groups. Results The incidence rate of suspected depression after 42 days and 3 months of delivery was lower in the intervention group than in the control group (P<0.05). Puerperae and their husbands in the intervention group obtained a higher subjective well⁃being score after 7 days, 42 days, and 3 months of delivery as compared with the control group, and both groups yielded an elevated tendency of subjective well⁃being score with observation time prolonging, as well as there was interaction effect between grouping and time (P<0.05). Conclusion DBL curriculum learning by puerperae and their husbands can decrease the incidence rate of suspected depression in puerperae, and improve subjective well⁃being of puerperae and their husbands, which is worthy of promotion.