Objective To analyze the research hotspots and trends of whiplash injury (WI) based on bibliometrics.Methods Literature related to WI was retrieved from the database of Web of Science™ Core Collection from 1st January, 1999 to 31st December, 2022. The CiteSpace 6.1.R6 software was used to analyze change trends of the annual number of publications, number of publications by countries/regions, number of publications by research institutions, number of publications by authors, and to perform keywords co-occurrence analysis, keywords cluster analysis, and keywords burstness analysis. Results There were 2790 literature related to WI included by the database of Web of Science™ Core Collection form 1999 to 2022 in total, and the annual number of publications generally exhibited a fluctuating upward trend. The top three countries in terms of the number of publications were the United States of America, Australia, and Canada. The top three research institutions in terms of the number of publications were University of Queensland, University of Alberta, and University of Sydney. The top three authors in terms of the number of publications were Sterling M, Cote P, and Nijs J. There were 349 keywords, and keywords with the highest frequency were neck pain, whiplash injury, and injury. Eight clusters could be formed by the keywords, which were neck pain, cervical spine, proprioception, whiplash injury, recovery, validity, central sensitization, and magnetic resonance imaging. Quality of life, chronic whiplash injury, traumatic cerebral injury, moderate/severe disability, psychometric properties, and concussion, etc., would be the future research trends in WI research fields. Conclusion Research heat of WI generally exhibits a fluctuating upward trend, and research hotspots focus on neck pain, whiplash injury, proprioception, central sensitization, magnetic resonance imaging, and other aspects. Ameliorating patients' life quality, paying attention to psychological state in patients, promoting chronic WI patients' recovery, and identifying patients with WI and concomitant craniocerebral injury as soon as possible may be the future research trends of this fields.