Objective To investigate the therapeutic effect of sensory re⁃education training combined with mirror therapy on phantom limb pain in patients with lower limb amputation. Methods Sixty patients with phantom limb pain after lower limb amputation were selected as the research subjects, and they were divided into observation group or control group according to the random number table method, with 30 cases in each group. Patients of the observation group received sensory re⁃education training combined with mirror therapy for treatment, whereas the control group received only mirror therapy. Short Form of McGill Pain Questionnaire score with respect to Visual Analogue Scale (VAS) score, Present Pain Intensity (PPI) score, and Pain Rating Index (PRI) score, as well as Pittsburgh Sleep Quality Index (PSQI) score, and Hamilton Anxiety Scale (HAMA) score before treatment, and 1, 3, 6 weeks after treatment were compared between the two groups. Results There were statistically significant differences in VAS score, PPI score, PRI score, PSQI score, and HAMA score between the two groups (P<0.05). There was a tendency of decreases in VAS score, PPI score, PRI score, PSQI score, and HAMA score of patients in both groups with the prolonging of time (P<0.05). There was an interaction effect between grouping and time (P<0.05). The observation group exhibited a lower score of VAS 3 and 6 weeks after treatment, and lower scores of PPI, PRI, PSQI, and HAMA 1, 3, 6 weeks after treatment as compared with the control group (P<0.05). Conclusion Compared with single mirror therapy, applying sensory re⁃education training combined with mirror therapy can prominently reduce degree of phantom limb pain in patients after lower extremity amputation, ameliorate their sleep quality and anxiety, which is worthy of application and promotion.

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