ObjectiveTo explore the correlation of modified frailty index (mFI) with the occurrence risk of postoperative complications in elderly patients with gastric cancer. MethodsThe clinical data of 250 elderly patients with gastric cancer who underwent selective radical surgery for gastric cancer were retrospectively analyzed, and preoperative mFI was used to evaluate patients frailty states. Patients were assigned to occurrence group (n=45) or nonoccurrence group (n=205) according to whether complications within 30 days after surgery occurred or not. The clinical data were compared between patients of the two groups, and the influencing factors for the occurrence of complications within 30 days after surgery in elderly patients with gastric cancer were analyzed by using the multivariate Logistic regression model. ResultsCompared with the nonoccurrence group, the occurrence group exhibited increased intraoperative bleeding volume, elevated preoperative frailty proportion (mFI≥3 points, P＜0.05). The results of multivariate Logistic regression analysis revealed that long operation duration, preoperative frailty (mFI≥3 points) were the independent risk factors for the occurrence of complications within 30 days after surgery in elderly patients with gastric cancer (P＜0.05).ConclusionElderly gastric cancer patients with preoperative mFI≥3 points have increased risk of the occurrence of complications within 30 days after surgery. According to the results of mFI evaluation, individualized treatment and nursing regimens can be formulated before surgery, and active frailty management can reverse frailty states of elderly patients with gastric cancer, thereby decreasing the incidence rate of postoperative complications, and improving outcomes of patients after surgery.

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