Objective To explore the effect of APP⁃based continuing nursing mode on physical and neuropsychological development in premature infants within 24 months old. Methods A total of 199 premature infants who discharged from the Department of Neonatology were selected as the research subjects. According to length of hospital stay, the research subjects were assigned to control group (95 cases, receiving routine discharge management) or observation group (104 cases, implementing continuing nursing mode based on APP). The follow⁃up compliance rate of Neonatal Clinic, and physical and neuropsychological development in 3, 6, 9, 12, 18, and 24 months old were compared between premature infants of the two groups. Results The follow⁃up compliance rates of Neonatal Clinic in premature infants of 3, 6, 9, 12, 18, and 24 months old in the observation group were higher than those in the control group (P<0.05). At 3 months old, premature infants of the observation group obtained larger head circumference and body weight, and higher scores of grand motor behavior, fine motor behavior, language behavior, and personal⁃social behavior as compared with the control group (P<0.05), whereas there was no statistically significant difference in body length between the two groups (P>0.05). The observation group exhibited greater head circumference, body length, and body weight, as well as higher scores of adaptive behavior, grand motor behavior, fine motor behavior, language behavior, and personal⁃social behavior as compared with the control group at 6, 9, 12, 18, 24 months old (P<0.05). Conclusion APP⁃based continuing nursing mode can effectively elevate growth and development level and survival quality of premature infants.

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