Objective To construct the follow⁃up mode in children with liver transplantation based on Guangxi regional characteristics, and to explore its application effect. Methods A total of 120 children with liver transplantation were assigned to control group (66 cases) or observation group (54 cases). The control group received routine telephone follow⁃up mode for follow⁃up, whereas the observation group was followed up by follow⁃up mode in children with liver transplantation based on Guangxi regional characteristics. Caregiver care ability of Family Caregiver Task Inventory (FCTI) score, and medication compliance of immunosuppressive drugs in children in terms of Basel Assessment of Adherence to Immunosuppressive Medication Scale (BAASIS) score were compared between the two groups before discharge, and 1, 3, 6 months after discharge. The compliance of follow⁃up (follow⁃up compliance inventory score) 1 year after operation was compared between the two groups. Results There were statistically significant differences in scores of FCTI and BAASIS between the two groups, and there was a tendency to change over time, as well as there was an interaction effect between grouping and time; furthermore, the observation group yielded a lower FCTI score, while a higher BAASIS score as compared with the control group 3 and 6 months after discharge (P<0.05). The score of follow⁃up compliance inventory in the observation group was higher than that in the control group after 1 year of operation (P<0.05). Conclusion Follow⁃up mode in children with liver transplantation based on Guangxi regional characteristics can increase care ability of caregivers and improve children's follow⁃up compliance, as well as improve children's compliance of medication for immunosuppressive drugs.

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